Affinity DataIC50: 0.000200nMAssay Description:Dissociation constant against galectin-3 using competitive fluorescence polarizationMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0390nMAssay Description:Inhibition of 20S proteasome beta 5i (unknown origin) after 1 hr by fluorescence based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.300nMAssay Description:Inhibition of chymotrypsin-like activity of 20S proteasome in human HL60 cells using Suc-LLVYaminoluciferin as substrate after 2 hrs by fluorescence ...More data for this Ligand-Target Pair
Affinity DataIC50: 0.400nMAssay Description:Inhibition of human 20S immunoproteasome beta 5 chymotrypsin-like activityMore data for this Ligand-Target Pair
Affinity DataIC50: 0.400nMAssay Description:Inhibition of human 20S immunoproteasome beta 5 chymotrypsin-like activityMore data for this Ligand-Target Pair
Affinity DataIC50: 0.5nMAssay Description:Inhibition of chymotrypsin-like activity of human 20S proteasome using Suc-LLVY-MCA as substrate measured for 1 hr by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.600nMAssay Description:Inhibition of chymotrypsin-like activity of human 20S proteasome pretreated for 15 mins followed by Suc-Leu-Leu-Val-Tyr-AMC substrate addition by flu...More data for this Ligand-Target Pair
TargetA5LHX3/O14818/P20618/P25786/P25787/P25788/P25789/P28062/P28065/P28066/P28070/P28072/P28074/P40306/P49720/P49721/P60900/Q8TAA3/Q99436(Homo sapiens (Human))
Intermed Discovery Gmbh (Imd)
Curated by ChEMBL
Intermed Discovery Gmbh (Imd)
Curated by ChEMBL
Affinity DataIC50: 0.600nMAssay Description:Inhibition of human 20S proteasomeMore data for this Ligand-Target Pair
Affinity DataIC50: 0.688nMAssay Description:Inhibition of 20S proteasome beta 5c (unknown origin) after 1 hr by fluorescence based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.700nMAssay Description:Inhibition of chymotrypsin-like activity of human 20S proteasome pretreated for 15 mins followed by Suc-Leu-Leu-Val-Tyr-AMC substrate addition by flu...More data for this Ligand-Target Pair
Affinity DataIC50: 0.708nMAssay Description:Inhibition of 20S proteasome beta5 subunit (unknown origin) using Suc-LLVY-AMC as flurogenic substrate measured after 1 hr by fluorescence based anal...More data for this Ligand-Target Pair
Affinity DataIC50: 0.760nMAssay Description:Inhibition of chymotrypsin like activity of human 20S proteasome using Suc-Leu-Leu-Val-Tyr-AMC as substrate preincubated for 10 mins followed by subs...More data for this Ligand-Target Pair
Affinity DataIC50: 0.760nMAssay Description:Inhibition of chymotrypsin like activity of human 20S proteasome using Suc-Leu-Leu-Val-Tyr-AMC as substrate preincubated for 10 mins followed by subs...More data for this Ligand-Target Pair
Affinity DataIC50: 0.800nMAssay Description:Inhibition of chymotrypsin-like activity of human 20S proteasome using Suc-Leu-Leu-Val-Tyr-AMC as substrate preincubated for 15 mins followed by subs...More data for this Ligand-Target Pair
Affinity DataIC50: 0.800nMAssay Description:Inhibition of human 20S immunoproteasome beta 5 chymotrypsin-like activityMore data for this Ligand-Target Pair
Affinity DataIC50: 0.900nMAssay Description:Inhibition of chymotrypsin-like activity of human 20S proteasome pretreated for 15 mins followed by Suc-Leu-Leu-Val-Tyr-AMC substrate addition by flu...More data for this Ligand-Target Pair
Affinity DataIC50: 0.900nMAssay Description:Inhibition of chymotrypsin-like activity of human 20S proteasome using Suc-Leu-Leu-Val-Tyr-AMC as substrate preincubated for 15 mins followed by subs...More data for this Ligand-Target Pair
TargetA5LHX3/O14818/P20618/P25786/P25787/P25788/P25789/P28062/P28065/P28066/P28070/P28072/P28074/P40306/P49720/P49721/P60900/Q8TAA3/Q99436(Homo sapiens (Human))
Intermed Discovery Gmbh (Imd)
Curated by ChEMBL
Intermed Discovery Gmbh (Imd)
Curated by ChEMBL
Affinity DataIC50: 0.920nMAssay Description:Inhibition of chymotrypsin-like activity of human 20S proteasome using Suc-Leu Leu-Val-Tyr-AMC as substrate preincubated for 15 mins followed by subs...More data for this Ligand-Target Pair
Affinity DataIC50: 0.940nMAssay Description:Inhibition of 20S proteasome subunit beta-5i (unknown origin) using Ac-ANW-AMC as substrate and measured after 30 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of chymotrypsin-like activity of human 20S proteasome pretreated for 15 mins followed by Suc-Leu-Leu-Val-Tyr-AMC substrate addition by flu...More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of chymotrypsin-like activity of human 20S proteasome pretreated for 15 mins followed by Suc-Leu-Leu-Val-Tyr-AMC substrate addition by flu...More data for this Ligand-Target Pair
TargetA5LHX3/O14818/P20618/P25786/P25787/P25788/P25789/P28062/P28065/P28066/P28070/P28072/P28074/P40306/P49720/P49721/P60900/Q8TAA3/Q99436(Homo sapiens (Human))
Intermed Discovery Gmbh (Imd)
Curated by ChEMBL
Intermed Discovery Gmbh (Imd)
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of human 20S proteasomeMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of 20S proteasome beta5 subunit (unknown origin) using Suc-LLVY-AMC as flurogenic substrate measured after 1 hr by fluorescence based anal...More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of chymotrypsin like activity of human erythrocyte-derived 20S proteasome preincubated for 10 mins using Suc-LLVY-AMC as substrate after 6...More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of 26S proteasome beta 5 using LLVY as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 1.10nMAssay Description:Inhibition of 20S immunoproteasome beta 5i subunit in human peripheral blood monocyte using Ac-ANW-AMC as substrate in presence of PA28alpha by fluor...More data for this Ligand-Target Pair
Affinity DataIC50: 1.10nMAssay Description:Inhibition of 20S proteasome beta5 subunit (unknown origin) using Suc-LLVY-AMC as flurogenic substrate measured after 1 hr by fluorescence based anal...More data for this Ligand-Target Pair
Affinity DataIC50: 1.10nMAssay Description:Inhibition of chymotrypsin-like proteasome activity of human 20S proteasomeMore data for this Ligand-Target Pair
Affinity DataIC50: 1.10nMAssay Description:Inhibition of chymotrypsin like activity of human 20S proteasome using Suc-Leu-Leu-Val-Tyr-AMC as substrate preincubated for 10 mins followed by subs...More data for this Ligand-Target Pair
Affinity DataIC50: 1.10nMAssay Description:Inhibition of 20S proteasome subunit beta-5i (unknown origin) using Ac-ANW-AMC as substrate and measured after 30 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.10nMAssay Description:Inhibition of chymotrypsin-like activity of human 20S proteasome pretreated for 15 mins followed by Suc-Leu-Leu-Val-Tyr-AMC substrate addition by flu...More data for this Ligand-Target Pair
Affinity DataIC50: 1.10nMAssay Description:Inhibition of 20s immunoproteasome chymotrypsin-like activity in human peripheral blood monocyte using Ac-ANW-AMC as substrate in presence of proteas...More data for this Ligand-Target Pair
Affinity DataIC50: 1.12nMAssay Description:Inhibition of chymotrypsin like activity of human 20S proteasome using Suc-Leu-Leu-Val-Tyr-AMC as substrate preincubated for 10 mins followed by subs...More data for this Ligand-Target Pair
Affinity DataIC50: 1.15nMAssay Description:Inhibition of chymotrypsin like activity of human 20S proteasome using Suc-Leu-Leu-Val-Tyr-AMC as substrate preincubated for 10 mins followed by subs...More data for this Ligand-Target Pair
Affinity DataIC50: 1.16nMAssay Description:Inhibition of chymotrypsin like activity of human 20S proteasome using Suc-Leu-Leu-Val-Tyr-AMC as substrate preincubated for 10 mins followed by subs...More data for this Ligand-Target Pair
Affinity DataIC50: 1.16nMAssay Description:Inhibition of chymotrypsin like activity of human 20S proteasome using Suc-Leu-Leu-Val-Tyr-AMC as substrate preincubated for 10 mins followed by subs...More data for this Ligand-Target Pair
Affinity DataIC50: 1.20nMAssay Description:Inhibition of chymotrypsin like activity of human 20S proteasome using Suc-Leu-Leu-Val-Tyr-AMC as substrate preincubated for 10 mins followed by subs...More data for this Ligand-Target Pair
Affinity DataIC50: 1.20nMAssay Description:Inhibition of chymotrypsin like activity of human 20S proteasome using Suc-Leu-Leu-Val-Tyr-AMC as substrate preincubated for 10 mins followed by subs...More data for this Ligand-Target Pair
Affinity DataIC50: 1.20nMAssay Description:Inhibition of chymotrypsin like activity of human erythrocyte-derived 20S proteasome preincubated for 10 mins using Suc-LLVY-AMC as substrate after 6...More data for this Ligand-Target Pair
Affinity DataIC50: 1.20nMAssay Description:Inhibition of chymotrypsin like activity of human 20S proteasome using Suc-Leu-Leu-Val-Tyr-AMC as substrate preincubated for 10 mins followed by subs...More data for this Ligand-Target Pair
Affinity DataIC50: 1.20nMAssay Description:Inhibition of 20s immunoproteasome chymotrypsin-like activity in human peripheral blood monocyte using Ac-ANW-AMC as substrate in presence of proteas...More data for this Ligand-Target Pair
Affinity DataIC50: 1.20nMAssay Description:Inhibition of chymotrypsin-like activity of human 20S proteasome pretreated for 15 mins followed by Suc-Leu-Leu-Val-Tyr-AMC substrate addition by flu...More data for this Ligand-Target Pair
Affinity DataIC50: 1.20nMAssay Description:Inhibition of chymotrypsin like activity of 26S proteasome beta 5 subunit (unknown origin) by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.20nMAssay Description:Inhibition of human 20S immunoproteasome beta 5 chymotrypsin-like activityMore data for this Ligand-Target Pair
Affinity DataIC50: 1.20nMAssay Description:Inhibition of constitutive 20S proteasome beta 5 subunit in human erythrocytes using Ac-WLA-AMC as substrate in presence of PA28alpha by fluorimetry ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.20nMAssay Description:Inhibition of 20S proteasome subunit beta-5i (unknown origin) using Ac-ANW-AMC as substrate and measured after 30 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.20nMAssay Description:Inhibition of 20S proteasome beta5 subunit (unknown origin) using Suc-LLVY-AMC as flurogenic substrate measured after 1 hr by fluorescence based anal...More data for this Ligand-Target Pair
Affinity DataIC50: 1.20nMAssay Description:Inhibition of proteasome subunit beta-5i in human Raji cells using BODIPY-NC005 by fluorescent densitometryMore data for this Ligand-Target Pair
Affinity DataIC50: 1.20nMAssay Description:Inhibition of human platelet Thromboxane synthetaseMore data for this Ligand-Target Pair
Affinity DataIC50: 1.20nMAssay Description:Inhibition of chymotrypsin like activity of human 20S proteasome using Suc-Leu-Leu-Val-Tyr-AMC as substrate preincubated for 10 mins followed by subs...More data for this Ligand-Target Pair